A new study suggests that some widely used blood pressure medications may be associated with digestive problems, particularly the development of diverticulosis—a condition where small pouches form in the lining of the intestines.
According to Knowridge, researchers at Imperial College London conducted a large-scale genetic analysis involving data from around 750,000 individuals. The study focused on how blood pressure medications might affect the body beyond their intended function of lowering blood pressure.
The team analyzed the genetic effects of three major types of antihypertensive medications:
- ACE inhibitors
- Beta-blockers
- Calcium channel blockers (specifically non-dihydropyridines)
Calcium channel blockers help relax blood vessels, allowing blood to flow more easily. However, researchers found a possible link between non-dihydropyridine calcium channel blockers and a higher risk of bowel issues such as diverticulosis. This could be due to the drug’s influence on the smooth muscles in the intestines, which are responsible for moving food along the digestive tract.
“People should not stop taking their blood pressure medication without talking to their doctor first,” said Dr. Dipender Gill, the lead author of the study. “Stopping blood pressure medicine suddenly can be very dangerous and could lead to serious health problems like strokes or heart attacks.”
The researchers emphasize that while this association is worth noting, it’s not a cause for alarm or immediate change in treatment. The medications remain vital in managing high blood pressure and preventing cardiovascular events.
Doctors and patients are encouraged to stay informed, but not to make any medication changes without medical consultation. Future studies will likely look into how to reduce these potential risks without compromising blood pressure control.
Article updated 4 weeks ago. Content is written and modified by multiple authors.
